Month: June 2020

Comparative study to evaluate efficacy of Remdesivir and Lopinavir/ritonavir in COVID-19 patients

Abstract Coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2. (SARS-CoV-2) SARS-CoV-2 first emerged in Wuhan China in December 2019 and rapidly spread worldwide. Infections have risen to 4 million with the outbreak being classified as a pandemic. Unfortunately, there is no established cure for the disease necessitating compassionate use of …

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Managing Complications of COVID-19: Acute Kidney Injury, Myocarditis, Clotting Abnormalities.

Abstract In March 2020, the World Health Organization declared COVID-19 infection a pandemic. The management and treatment plan have been based on previous evidence on use during viral pandemics such as Spanish flu, Ebola Virus, Middle East Respiratory Syndrome. SARS-CoV-2 presents a lot of complications as the disease progresses and most of these complications contribute …

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A review into the Therapeutic Rationale for Use of Lopinavir/Ritonavir in COVID-19 Patients

Abstract With the current outbreak of coronavirus disease (COVID 19) and no specific therapy for its management, varied drugs and drug combinations have been tried. This has led to repurposing of different drugs which have been in use for varied diseases e.g. Lopinavir/ritonavir which is used in Human Immunodeficiency Virus (HIV) management among other therapies. …

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Infection Prevention and Control as a Response to COVID-19: Hand Hygiene and Fecal Waste Disposal

Abstract: Good sanitation and hygiene have been recommended as an effective response in managing and controlling transmission of Coronavirus disease (COVID-19). Adherence to given recommendations reduces the transmission rate and lowers overall infections and number of cases in a disease. Hand washing has been identified to be one of the key measures that will help …

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